TOPIC

Total No. of hours

practical

Tutorial/Practical

IV-Cytogenetics

1. cell cycle and cell division (mitosis  meiosis).
2. Gametogenesis(oogenesis &spermatogenesis).
3. structure of  chromosomes.
4. chromosomal study& karyotyping.
5. chromosomal bands:  G banding, fluorescence in situ hybridization.
6. Sex chromatin (Barr body ).
7. chromosomal aberrations : 

  a-numerical abnormalities :

i-aneuploidy (monosomy,trisomy).

ii-polyploidy (triploidy , tetraploidy, endoreduplication).

  b-structural   abnormalities :

1. translocation.
2. deletion.
3. inversion.  
4. insertion.
5. isochromosome.
6. dicentric chromosome.
7. ring chromosome.
8. duplication. 
9. fragile x chromosome clinical correlations with cytogenetic disorders.

12

6

6